Lemur: Harmonizing Natural Language and Code for Language Agents

We introduce Lemur and Lemur-Chat, openly accessible language models optimized for both natural language and coding capabilities to serve as the backbone of versatile language agents. The evolution from language chat models to functional language agents demands that models not only master human interaction, reasoning, and planning but also ensure grounding in the relevant environments. This calls for a harmonious blend of language and coding capabilities in the models. Lemur and Lemur-Chat are proposed to address this necessity, demonstrating balanced proficiencies in both domains, unlike existing open-source models that tend to specialize in either. Through meticulous pre-training using a code-intensive corpus and instruction fine-tuning on text and code data, our models achieve state-of-the-art averaged performance across diverse text and coding benchmarks among open-source models. Comprehensive experiments demonstrate Lemur's superiority over existing open-source models and its proficiency across various agent tasks involving human communication, tool usage, and interaction under fully- and partially- observable environments. The harmonization between natural and programming languages enables Lemur-Chat to significantly narrow the gap with proprietary models on agent abilities, providing key insights into developing advanced open-source agents adept at reasoning, planning, and operating seamlessly across environments. https://github.com/OpenLemur/Lemu

Extraction, Identification, Modification, and Antibacterial Activity of Histone from Immature Testis of Atlantic salmon

In the present study, histone from immature testis of Atlantic salmon was extracted and identified, and its antibacterial activity after enzymolysis was investigated. Histone extracted from Atlantic salmon (Salmo salar) testis using the acid extraction method was successfully identified by LC-MS/MS, and revealed significant inhibitory activity on both the Gram-negative and Gram-positive bacteria. With a low concentration of 10 mg/mL, the observed inhibitory zone diameter (IZD) could significantly reach up to 15.23 mm. After modification of enzymatic hydrolysis by pepsin, histone could be digested to three fragments, while the antibacterial activity increased up to 57.7%. All the results suggested the leftovers from commercial fishing could be utilized for the extraction of antimicrobial peptides

A Novel Physically Based Distributed Model for Irrigation Districts’ Water Movement

The water movement research in irrigation districts is important for food production. Many hydrological models have been proposed to simulate the water movement on the regional scale, yet few of them have comprehensively considered processes in the irrigation districts. A novel physically based distributed model, the Irrigation Districts Model (IDM), was constructed in this study to address this problem. The model combined the 1D canal and ditch flow, the 1D soil water movement, the 2D groundwater movement, and the water interactions among these processes. It was calibrated and verified with two-year experimental data from Shahaoqu Sub-Irrigation Area in Hetao Irrigation District. The overall water balance error is 2.9% and 1.6% for the two years, respectively. The Nash–Sutcliffe efficiency coefficient (NSE) of water table depth and soil water content is 0.72 and 0.64 in the calibration year and 0.68 and 0.64 in the verification year. The results show good correspondence between the simulation and observation. It is practicable to apply the model in water movement research of irrigation districts